2021 Scientific Retreat- Session 10

Session 10: Widening the Aperture; New Approaches for Immunotherapy in Prostate Cancer 
Friday, November 5, 2021 | 8:50 AM – 10:35 AM PST 

Moderator: Amy Moran, PhD, Oregon Health & Science University 

A T Cell Intrinsic Role for Androgen Receptor Signaling and Immunotherapy Resistance 
Amy Moran, PhD, Oregon Health & Science University 

Checkpoint Immunotherapy in mCRPC with CDK12-Loss 
Ajjai Alva, MD, University of Michigan 

MGC018, an Anti-B7-H3 Antibody-Drug Conjugate (ADC), in Patients With mCRPC: Preliminary Results of Phase 1 Cohort Expansion 
Chet Bohac, PharmD, MD, MSc, MacroGenics, Inc. 

Targeting DLL3 with a Bi-Specific T Cell Engager: AMG 757 in De Novo and Treatment-Emergent Small Cell Neuroendocrine Prostate Cancer 
Rahul Aggarwal, MD, University of California, San Francisco 

Advancing the Frontiers of T-Cell Redirecting Agents in Prostate Cancer 
Oliver Sartor, MD, Tulane University