Challenge Awards
Class of 2022


2022 Stupski Foundation-PCF Challenge Award

Debunking the Frailty-SarcopenIa-ADT Axis in MEtastatic Prostate CanceR with MultiCompenent Exercise: The FIERCE Trial

Principal Investigator: Christina Dieli-Conwright, PhD, MPH (Dana-Farber Cancer Institute)

Co-Investigators: Rebekah Wilson, PhD (Dana-Farber Cancer Institute), Alicia Morgans, MD (Dana-Farber Cancer Institute), Michael Rosenthal, MD, PhD (Dana-Farber Cancer Institute), Hajime Uno, PhD (Dana-Farber Cancer Institute), Matthew Vander Heiden, MD, PhD (Dana-Farber Cancer Institute)

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2022 Patrice & Precious Motsepe-PCF VAlor Challenge Award

Developing and Translating Innovative Strategies to Therapeutically Target Prostate Cancer Lineage Plasticity

Principal Investigators: David Goodrich, PhD (Roswell Park Comprehensive Cancer Center), Gurkamal Chatta, MD (Roswell Park Comprehensive Cancer Center), Dean Tang, PhD (Roswell Park Comprehensive Cancer Center), Dominic Smiraglia, PhD (Roswell Park Comprehensive Cancer Center)

Co-Investigators: Mark Long, PhD (Roswell Park Comprehensive Cancer Center), Himisha Beltran, MD (Dana-Farber Cancer Institute)

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2022 PCF Challenge Award

Project Title: Targeting Lipid Metabolism and Diet in Patients with Locally Advanced Prostate Cancer

Principal Investigator: Massimo Loda, MD (Weill Cornell Medicine)

Co-Investigators: David Nanus, MD (Weill Cornell Medicine), Christopher Barbieri, MD, PhD (Weill Cornell Medicine), Caroline Ribeiro, PhD, MSc (Weill Cornell Medicine), Marcus DaSilva Goncalves, MD, PhD (Weill Cornell), Katie Hootman, PhD (Weill Cornell Medicine), James Kelly, PhD (Weill Cornell Medicine), Karla Ballman, PhD, MS (Weill Cornell Medicine), Pier Vitale Nuzzo, MD, PhD (Weill Cornell Medicine), Steve Plymate, MD (University of Washington) Johan Swinnen, PhD (International Food Policy Research Institute)

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2022 John Black Charitable Foundation-PCF Challenge Award

Epitranscriptomic Determinants of Treatment Resistance in Prostate Cancer

Principal Investigator: Nigel Mongan, PhD (University of Nottingham)

Co-Investigators: Corinne Woodcock (University of Nottingham), Nathan Archer, PhD (University of Nottingham), Rupert Fray, PhD (University of Nottingham), Victoria James, PhD (University of Nottingham), Jennie Jeyapalan, PhD (University of Nottingham), Jennifer Lothion-Roy BVM BVS (University of Nottingham), Anna Harris BSc (University of Nottingham)

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2022 Michael & Lori Milken Family Foundation-PCF Challenge Award

Activating the NLRP3 Inflammasome to Treat Advanced Prostate Cancer

Principal Investigators: Akash Patnaik, MD, PhD (University of Chicago), Amy Moran, PhD (Oregon Health & Science University), David Sykes, MD, PhD (Massachusetts General Hospital)

Co-Investigators: Peter Sorger, PhD (Harvard Medical School), Jia-Ren Lin, PhD, MS (Harvard Medical School), Michael Haffner, MD, PhD (Fred Hutchinson Cancer Research Center), Colby Thaxton, MD, PhD (Northwestern University), Massimo Loda, MD (Weill Cornell Medicine), Theodore Karrison, PhD, MS (University of Chicago), Thomas Gajewski, MD, PhD (University of Chicago)

Young Investigators: Kiranj Chaudagar, PhD (University of Chicago), Mindy Graham, PhD (Johns Hopkins School of Medicine), Taghreed Hirz, PhD (Massachusetts General Hospital), Shenglin Mei, PhD (Harvard Medical School)

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