Challenge Awards Class of 2023
2023 Bayer-PCF Darolutamide Challenge Award
Darolutamide to Augment Radiotheranostic Therapy in Biochemically Recurrent Prostate Cancer (DART-BCR)
Principal Investigators: Praful Ravi, MD (Harvard: Dana-Farber Cancer Institute), David Einstein, MD (Beth Israel Deaconess Medical Center)
Young Investigator: Daniel Fein, MD (Beth Israel Deaconess Medical Center)
Co-Investigators: Heather Jacene, MD (Dana-Farber Cancer Institute), Mary-Ellen Taplin, MD (Dana-Farber Cancer Institute), Jacob Berchuck, MD (Dana-Farber Cancer Institute), Steve Balk, MD (Beth Israel Deaconess Medical Center)
2023 Durden Foundation-PCF Challenge Award
Characterizing Imaging, Genomic and Immune Predictors of 177Lu-PSMA (Lu-PSMA) and Olaparib Response in Patients with Metastatic Castration Resistant Prostate Cancer (mCRPC)
Principal Investigators: Shahneen Sandhu, MBBS (The University of Melbourne), Belinda Parker, PhD (University of Melbourne)
Co-Investigators: Michael Hofman, MBBS (University of Melbourne), Nicole Haynes, PhD (University of Melbourne), David Quigley, PhD (University of California San Francisco), Alexander Wyatt, PhD (University of British Columbia), Anna Trigos, PhD (University of Melbourne), Louise Emmett, MD (St Vincent’s Hospital), Anis Hamid, MBBS (Peter MacCallum Cancer Centre), Ramyar Molania, PhD (University of Melbourne), Anthony Joshua, MBBS, PhD (St Vincent’s Hospital), Andrei Gafita, MD, PhD (Johns Hopkins University), Felix Feng, MD (University of California San Francisco), William Chen, MD (University of California San Francisco), Paul Neeson, PhD (University of Melbourne)
Young Investigator: Richard Rebello, PhD (University of Melbourne)
2023 John and Daria Barry Foundation- PCF VAlor Challenge Award
Germline Influence on Prostate Cancer Metastasis and Response to Androgen Deprivation Therapy
Principal Investigators: Tyler Seibert, MD, PhD (University of California San Diego), Rana McKay, MD (University of California San Diego), Paul Boutros, PhD, MBA (University of California Los Angeles)
Young Investigators: Roni Haas, PhD (University of California Los Angeles), Sophia Kamran, MD (Massachusetts General Hospital)
Co-Investigators: Felix Feng, MD (University of California San Francisco), Phuoc Tran, MD, PhD (University of Maryland), Alan Pollack, MD, PhD (University of Miami), Daniel Spratt, MD (University Hospitals / Case Western), Elai Davicioni, PhD (Veracyte), Isla Garraway, MD, PhD (University of California Los Angeles), Jason Vassy, MD, MPH (VA Boston Healthcare System)
2023 PCF Hamptons Coalition-PCF Challenge Award
Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance in Metastatic Prostate Cancer
Principal Investigators: Karen Sfanos, PhD (Johns Hopkins University), Cathy Marshall, MD, MPH (Johns Hopkins Medicine), Mark Markowski, MD, PhD (Johns Hopkins Medicine), Jason Ridlon, PhD (University of Illinois Urbana-Champaign), Young Investigator: Angélica Cruz-Lebrón, PhD (Johns Hopkins University)
Co-Investigators: Hao Wang, PhD (Johns Hopkins University), Isaac Cann, PhD (University of Illinois), Joseph Irudayaraj, PhD (University of Illinois)
Collaborators: Samuel Denmeade, MD (Johns Hopkins Medicine)
2023 Regeneron – PCF Special Challenge Award
A Pilot Presurgical Trial of REGN5678 (Anti-PSMAxCD28) In Patients with High-Risk, Localized Prostate Cancer Followed by Radical Prostatectomy
Principal Investigators: Padmanee Sharma, MD, PhD (The University of Texas MD Anderson Cancer Center), Sumit Subudhi, MD, PhD (The University of Texas MD Anderson Cancer Center), Brian Chapin, MD (The University of Texas MD Anderson Cancer Center), Bilal Siddiqui, MD (The University of Texas MD Anderson Cancer Center)