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FGFR Inhibition to Develop Effective Combination Therapies..
University:
The University of Texas MD Anderson Cancer Center
Understanding the molecules and mechanisms that contribute..
Andreas Varkaris, MD:
The University of Texas MD Anderson Cancer Center
Mentors:
Gary Gallick, PhD and Christopher Logothetis, MD
Diet and Progression of Prostate Cancer among..
University:
Roswell Park Cancer Institute, New York
One of the challenges in prostate cancer..
Barry Taylor, PhD:
University of California, San Fransisco
Mentors:
Charles Sawyers, MD and Chris Sander, PhD
Dr. Srivastava is studying malignant cells from..
Abhishek Srivastava, MD:
University of Michigan
Mentor:
Ashutosh Tewari, MD, PhD
For prostate cancer patients at higher risk..
Timothy Showalter, MD:
University of Virginia
Mentors:
Adam Dicker, MD, PhD and Theresa Hyslop, PhD
It is unclear why prostate cancer selectively..
Yusuke Shiozawa, MD, PhD:
University of Michigan
Mentor:
Russell Taichman, DMD
Dr. Roychowdhury works to underline and identify..
Sameek Roychowdhury, MD, PhD:
The Ohio State University
Mentors:
Arul Chinnaiyan, MD, PhD and Ken Pienta, MD
Ipilimumab is a cancer immunotherapy that has..
Sumit Subudhi, MD, PhD:
M. D. Anderson Cancer Center
Mentors:
James Allison, PhD, Padmanee Sharma, MD, PhD
Proposal Title:
Improving Patient Selection for Immune Checkpoint Therapy: Maximizing Benefit and Minimizing Toxicities
The success of next-generation androgen receptor (AR)..
Dana Rathkopf, MD:
Memorial Sloan-Kettering Cancer Center
Mentors:
Howard Scher and MD Neal Rosen, MD, PhD
Few options remain for prostate cancer patients..
Tanya Stoyanova, PhD:
University of California at Los Angeles
Mentors:
Owen Witte, MD
Proposal Title:
Proteolytically Cleaved Receptors as Oncogenes and Therapeutic Targets in Advanced Castration Resistant Prostate Cancer
Periprostatic Fat as a Promoter of Prostate..
University:
NorthShore University HealthSystem Research Institute, Illinois
A critical unmet need for prostate cancer..
Antoinette Perry, PhD:
Trinity College Dublin – Institute of Molecular Medicine
Mentors:
William Watson, PhD and Donal Hollywood, MD PhD
Augmenting OX40 Immunotherapy in Men with Advanced..
University:
Providence Portland Medical Center, Oregon
The immune system is a powerful natural..
Matthias Stephan, MD, PhD:
Fred Hutchinson Cancer Research Center
Mentor:
Peter Nelson, MD
Proposal Title:
In Vivo Programming of Prostate Tumor-Specific T cells using Synthetic Nanoparticles
The Gleason score (derived from the microscopic..
Kathryn L. Penney, ScD:
Harvard Medical School
Mentors:
Massimo Loda, MD and Meir J. Stampfer, MD, DrPH
Some prostate cancer patients who undergo radiation..
Daniel Spratt, MD:
University of Michigan
Mentors:
Charles Sawyers, MD
Proposal Title:
Androgen Receptor Signaling Post-Radiotherapy: A Novel Non-Invasive Predictive Biomarker for Locally Advanced and Castrate Resistant Prostate Cancer
Circulating Tumor Cells (CTCs) detach from metastatic..
Richard Lee, MD, PhD:
Massachusetts General Hospital Cancer Center
Mentor:
Matthew R. Smith, MD, PhD
Targeting Neurogenesis in Prostate Cancer The prostate..
The immune system has the power to..
Jinjun Shi, PhD:
Brigham and Women’s Hospital, Harvard Medical School
Mentors:
Omid Farokhzad, MD, Ulrich von Andrian, MD, PhD
Proposal Title:
mRNA-Based Immuno-Nanotherapeutics for Advanced Prostate Cancer Treatment
T-cells are a type of fighter blood..
Jihyun Lee, PhD:
University of Pennsylvania
Mentor:
Carl June, MD
Precision medicine is the generation of individualized..
Nikolaus Schultz, PhD:
Memorial Sloan-Kettering Cancer Center
Mentors:
Charles Sawyers, MD, Chris Sander, PhD
Proposal Title:
A Genomics-Guided Decision Support System for the Treatment of Prostate Cancer
To address the challenges of resistance to..
Maria Karlou, PhD:
University of Athens
Mentor:
Christopher Logothetis, MD
The Mesenchymal-to-Epithelial Transition (MET) as a Novel..
Designation:
Professor of Cancer Biology, Department of Surgery
University:
Harvard Medical School
Dana-Farber/Harvard Cancer Center
Long non-coding RNAs (lncRNA) are a recently..
Anirban Sahu, PhD:
University of Michigan
Mentor:
Arul Chinnaiyan, MD, PhD
Proposal Title:
The Role of Long Noncoding RNA SChLAP1 in Aggressive Prostate Cancer
Dr. Joshu and colleagues previously observed that..
Corinne Joshu, PhD:
Johns Hopkins University
Mentors:
Elizabeth Platz, ScD and Angelo DeMarzo, MD, PhD
The androgen receptor (AR) is the engine..
Brian Olson, PhD:
University of Wisconsin Carbone Cancer Center
Mentors:
Douglas McNeel, MD, PhD, Glenn Liu, MD
Proposal Title:
Targeting Resistance to Androgen Deprivation Therapies using Immunotherapies Targeting the Androgen Receptor
Genomic rearrangements that lead to the juxtaposition..
Michael Haffner, MD:
Johns Hopkins University
Mentor:
Srinivasan Yegnasubramanian, MD, PhD
BRCA is a gene that mediates DNA..
David Olmos, MBBS, MSc, PhD:
Spanish National Cancer Research Centre
Mentors:
Johann de Bono, MD, PhD, Manuel Hidalgo, MD, PhD
Proposal Title:
Integration of Clinical, Molecular and Biological Characteristics to Define an Aggressive Subtype of Prostate Cancer Based on Deficient Homologous Recombination
The first medical treatment for metastatic prostate..
Award1:
The 2011 Bonnie Pfeifer Evans – PCF Young Investigator Award (second year)
Award2:
The 2011 Todd Boehly – PCF Young Investigator Award
Andrew Goldstein, PhD:
University of California, Los Angeles
Mentor:
Owen Witte, MD
Target identification Combining In Vivo Tissue Transformation..
Designation:
Distinguished Professor of Microbiology, Immunology, and Molecular Genetics
President's Chair in Developmental Immunology
University:
David Geffen School of Medicine
University of California, Los Angeles
Dr. Beltran’s research will help define the..
Himisha Beltran, MD:
Weill Cornell Medical College – New York, NY
Co-Mentor:
David Nanus, MD, Medical Director of the Genitourinary Oncology Program and Chief of the Division of Hematology and Medical Oncology at Weill Cornell Medical College.
Co-Mentor:
Mark Rubin, MD, Professor of Pathology and Laboratory Medicine, Director of Translational Research Laboratory Services, and Vice Chairman for Experimental Pathology at Weill Cornell Medical College.
The landscape of therapeutic options for men..
Matthew Cooperberg, MD:
University of California, San Francisco
Mentors:
Peter Caroll, MD and Charles Ryan, MD
Todd M. Morgan, M.D. is a urological..
Todd Morgan, MD:
University of Michigan
Mentors:
Arul Chinnaiyan, MD, PhD, Russell Taichman, DMD, DMSc
Proposal Title:
Defining the Role of the HGF/c-MET Axis as a Mediator of Therapeutic Resistance in Advanced Prostate Cancer
Niphatenones a Completely New Class of Androgen..
Designation:
Senior Scientist, Michael Smith Genome Sciences Centre, BC Cancer Agency
Honorary Associate Professor
University:
University of British Columbia
Therapies targeting the androgen receptor (AR) are..
Rohit Malik, PhD, MSc:
Research fellow, University of Michigan
Mentor:
Arul Chinnaiyan, MD, PhD
Proposal Title:
Characterization and Therapeutic Targeting of Androgen Receptor Co-activators in Castration Resistant Prostate Cancer
More than 50% of prostate cancers have..
Award1:
The 2011 Cayre Family Foundation – PCF Young Investigator Award (second year)
(first year)
Award2:
The 2011 Robert Kraft – PCF Young Investigator Award (third year)
John Chadwick Brenner, MSc, PhD:
University of Michigan
Mentor:
Arul Chinnaiyan, MD, PhD