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Gene fusions in prostate cancer are early..
Ram S. Mani, PhD:
University of Michigan – Ann Arbor, MI
Mentor:
Arul Chinnaiyan, MD, PhD, Howard Hughes Medical Institute Investigator, Director of Pathology Research Informatics, Director of Cancer Bioinformatics, S.P. Hicks Endowed Professor of Pathology, American Cancer Society Research Professor, Professor of Urology, at the University of Michigan.
The speed of sequencing the entire DNA..
Award:
The 2010 Stewart Rahr – PCF Young Investigator Award
Christopher Maher, PhD:
University of Michigan – Ann Arbor, MI
Mentor:
Arul Chinnaiyan, MD, PhD, Howard Hughes Medical Institute Investigator, Director of Pathology Research Informatics, Director of Cancer Bioinformatics, S.P. Hicks Endowed Professor of Pathology, American Cancer Society Research Professor, Professor of Urology, at the University of Michigan.
Statins are cholesterol-lowering medications used widely to..
Stanley Liauw, MD:
University of Chicago – Chicago, IL
Co-Mentor:
Ralph Weichselbaum, MD, Chairman, Radiation and Cellular Oncology Department, Director, Chicago Tumor Institute, and Director, Ludwig Center for Metastasis Research, University of Chicago.
Co-Mentor:
Walter Stadler, MD, Director, Genitourinary Program, Chair, Cancer Research Center's Clinical Trials Review Committee, and Associate Dean for Clinical Research, University of Chicago.
Immunotherapy activates the body’s own immune system..
Joshua Lang, MD, MS:
University of Wisconsin Carbone Comprehensive Cancer Center – Madison, WI
Mentor:
Douglas McNeel, MD, PhD, Associate Professor of Medicine, Section of Hematology/Oncology at the University of Wisconsin Carbone Comprehensive Cancer Center.
Decades of research have revealed the cascade..
Andrew C. Hsieh, MD:
University of California, San Francisco – San Francisco, CA
Mentor:
Davide Ruggero, PhD, Assistant Professor, School of Medicine, University of California, San Francisco.
There is no curative treatment available for..
Huihui Ye, MD:
Harvard Medical School: Beth Israel Deaconess Medical Center
Mentors:
Steven Balk, MD, PhD
Proposal Title:
Investigation of Molecular Mechanisms and Biomarkers of Treatment Resistance in a Randomized, Phase 2 Neoadjuvant Intense Androgen Deprivation Trial in Patients with Localized, Intermediate to High Risk Prostate Cancer
The risk of developing and dying from..
Kosj Yamoah, MD, PhD:
Thomas Jefferson University
Mentors:
Adam Dicker, MD, PhD, Timothy Rebbeck, PhD
Proposal Title:
Identification and Validation of a Biomarker Signature that can Improve Predictability of Aggressive Disease in Men of African Descent with Prostate Cancer
Understanding the biology of how prostate cancer..
Kamlesh Yadav, PhD :
Icahn School of Medicine at Mount Sinai
Mentors:
Ash Tewari, MD
Proposal Title:
Rational Design of Effective Prostate Cancer Combination Therapies
Metastatic prostate cancer is essentially incurable and..
Kathryn Wilson, ScD:
Harvard School of Public Health
Mentors:
Lorelei Mucci, ScD, Matthew Smith, MD, PhD
Proposal Title:
Bone Metabolism and Bone Metastases in Prostate Cancer
Androgens (testosterone and related sex hormones) drive..
Hannelore Heemers, PhD:
Roswell Park Cancer Institute – Buffalo, NY
Mentor:
James Mohler, MD, Professor and Chairman of the Department of Urology and Associate Director and Senior Vice President for Translational Research at Roswell Park Cancer Institute.
Prostate Specific Antigen (PSA) screening is widely..
Julia Hayes, MD:
Dana-Farber Cancer Institute – Boston, MA
Co-Mentor:
Philip Kantoff, MD, Chief Clinical Research Officer, Director of the Lank Center of Genitourinary Oncology and Chief of the Division of Solid Tumor Oncology at Dana-Farber Cancer Institute.
Co-Mentor:
Michael Barry, MD, Director of the Health Services Research Program and Chief of the General Medicine Unit at Massachusetts General Hospital.
The molecular processes that predict who will..
Daniel Hamstra, MD, PhD:
University of Michigan – Ann Arbor, MI
Mentor:
Kenneth Pienta, MD, Professor, Departments of Internal Medicine and Urology, Associate Dean for Clinical and Translational Research, American Cancer Society Clinical Research Professor, Director, Experimental Therapeutics, Michigan Center for Translational Pathology, Director, Michigan Institute for Clinical and Health Research, at the University of Michigan.
Dr. Hammers has initiated a project to..
Hans Hammers, MD, PhD:
Johns Hopkins University Medical School – Baltimore, MD
Mentor:
Michael Carducci, MD, Professor of Oncology and Urology, Co-Director Genitourinary Prostate Cancer Program, Co-Director Chemical Therapeutics, at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University.
Obesity increases the risk of developing prostate..
David S. Finley, MD:
University of California, Los Angeles – Los Angeles, CA
Mentor:
Robert Reiter, MD, Professor, Urology, Molecular Biology, Co-Director of the Prostate and Genitourinary Oncology Program, Jonsson Comprehensive Cancer Center, Director of Urologic Research, at the University of California, Los Angeles .
Radiation therapy in combination with medicines that..
Robert Den, MD:
Kimmel Cancer Center, Thomas Jefferson University – Philadelphia, PA
Co-Mentor:
Karen Knudsen, PhD, Associate Professor, Departments of Cancer Biology and Urology at the Kimmel Cancer Center, Thomas Jefferson University.
Co-Mentor:
Adam Dicker, MD, PhD, Interim Chair and Professor, Radiation Research and Translational Biology, at the Kimmel Cancer Center, Thomas Jefferson University.
Despite advances in the early detection and..
Brett S. Carver, MD:
Memorial Sloan-Kettering Cancer Center – New York, NY
Mentor:
Charles Sawyers, MD, Professor of Medicine, Chair, Human Oncology and Pathogenesis Program; Marie-Josee and Henry R. Kravis Chair at Memorial Sloan-Kettering Cancer Center
A Novel Human-to-Mouse-to-Human Approach for the Elucidation..
Award:
First-time PCF Award Recipient
University:
Columbia University Medical Center
Exploration of the Relationship between In Vivo..
University:
Peter MacCallum Cancer Centre, Australia
Matthew Smith, M.D., Ph.D. is the Director..
University:
Massachusetts General Hospital
New therapeutics are urgently needed for hormone..
Justine Bruce, MD:
University of Wisconsin Carbone Comprehensive Cancer Center – Madison, WI
Mentor:
Glenn Liu, MD, Associate Professor of Medicine, Section of Medical Oncology and Hematology, at the University of Wisconsin Carbone Comprehensive Cancer Center.
A Nano-Structured Platform for Enhanced Detection of..
University:
University of California, Los Angeles
Implications of Obesity in Prostate Cancer Recurrence..
University:
The University of Texas MD Anderson Cancer Center
Technical advances have led to the identification..
Award1:
The 2011 Earle I. Mack – PCF young Investigator Award (second year)
Award2:
2011 Rebecca and Nathan Milikowsky – PCF young Investigator Award (third year)
Timothy Yap, BSc (Hons), MBBS, MRCP:
The Institute of Cancer Research, The Royal Marsden Hospital
Mentor:
Johann De Bono, MD, PhD
FGFR Inhibition to Develop Effective Combination Therapies..
University:
The University of Texas MD Anderson Cancer Center
Understanding the molecules and mechanisms that contribute..
Andreas Varkaris, MD:
The University of Texas MD Anderson Cancer Center
Mentors:
Gary Gallick, PhD and Christopher Logothetis, MD
Diet and Progression of Prostate Cancer among..
University:
Roswell Park Cancer Institute, New York
One of the challenges in prostate cancer..
Barry Taylor, PhD:
University of California, San Fransisco
Mentors:
Charles Sawyers, MD and Chris Sander, PhD
Dr. Srivastava is studying malignant cells from..
Abhishek Srivastava, MD:
University of Michigan
Mentor:
Ashutosh Tewari, MD, PhD
For prostate cancer patients at higher risk..
Timothy Showalter, MD:
University of Virginia
Mentors:
Adam Dicker, MD, PhD and Theresa Hyslop, PhD
It is unclear why prostate cancer selectively..
Yusuke Shiozawa, MD, PhD:
University of Michigan
Mentor:
Russell Taichman, DMD
Dr. Roychowdhury works to underline and identify..
Sameek Roychowdhury, MD, PhD:
The Ohio State University
Mentors:
Arul Chinnaiyan, MD, PhD and Ken Pienta, MD
Ipilimumab is a cancer immunotherapy that has..
Sumit Subudhi, MD, PhD:
M. D. Anderson Cancer Center
Mentors:
James Allison, PhD, Padmanee Sharma, MD, PhD
Proposal Title:
Improving Patient Selection for Immune Checkpoint Therapy: Maximizing Benefit and Minimizing Toxicities
The success of next-generation androgen receptor (AR)..
Dana Rathkopf, MD:
Memorial Sloan-Kettering Cancer Center
Mentors:
Howard Scher and MD Neal Rosen, MD, PhD
Few options remain for prostate cancer patients..
Tanya Stoyanova, PhD:
University of California at Los Angeles
Mentors:
Owen Witte, MD
Proposal Title:
Proteolytically Cleaved Receptors as Oncogenes and Therapeutic Targets in Advanced Castration Resistant Prostate Cancer
Periprostatic Fat as a Promoter of Prostate..
University:
NorthShore University HealthSystem Research Institute, Illinois
A critical unmet need for prostate cancer..
Antoinette Perry, PhD:
Trinity College Dublin – Institute of Molecular Medicine
Mentors:
William Watson, PhD and Donal Hollywood, MD PhD