Charles Chan

About Charles Chan

• Engraftment of prostate cancer in bone heralds a lethal form of the disease.
• New targets are needed for the treatment of prostate cancer in bone and to prevent bone localization altogether.
• Dr. Chan has discovered a type of metastatic prostate cancer stem cell that can home to bone and grow, causing increased morbidity.
• These investigations are aimed at inhibiting bone-derived factors that permit the localization and proliferation of prostate cancer in the bony environment.

What this means for patients: Dr. Chan proposes to study mechanisms of prostate cancer tumor engraftment in the bone. These studies will identify therapeutic targets to reduce this serious metastatic event.