Jennifer Schutzman
Many genes that are critical for proper embryonic development are disregulated in human cancers. For example, Sprouty genes (Spry1 and Spry2) are both critical for neuronal and early prostate gland...Read More
Philip Saylor
Hormonal therapy for prostate cancer causes weight gain, adversely alters cholesterol and other blood lipids, and is associated with increased risk for heart attacks and the development of type II...Read More
Edwin Posadas
Dr. Posadas’ research goal is to identify the molecular mechanisms of prostate cancer metastasis. A protein called FYN, which is a member of a cancer-causing gene family, was identified in...Read More
Akash Patnaik
Obesity has been identified as an important adverse prognostic factor for death due to prostate cancer. Dr. Patnaik will investigate the molecular mechanisms that link obesity to poor outcomes in...Read More
Nicholas Mitsiades
Src is a cancer-causing gene (oncogene) that is “switched” on in many adult human cancers including prostate cancer. The Src signaling pathway is activated in many patients whose cancer is...Read More
Neil Martin
There is increasing promise in the clinic for using targeted treatments for prostate cancer. Because of the specificity of emerging pharmacologic agents, it will be important to identify and treat...Read More
Ram S. Mani
Gene fusions in prostate cancer are early genetic alterations thought to initiate the process of cancer growth. These fusions are defined by the joining of two genes normally found in...Read More
Christopher Maher
The speed of sequencing the entire DNA content of human prostate cancer has increased by more than 100 times and the cost has been decreased by over 1,000 times in...Read More
Stanley Liauw
Statins are cholesterol-lowering medications used widely to reduce the risk of cardiovascular disease and related death. There is mounting interest in the potential anti-cancer effects of statins if used in...Read More
Joshua Lang
Immunotherapy activates the body’s own immune system to attack tumor cells. Dr. Lang’s research proposal focuses on increasing the power of immunotherapy for the treatment of advanced prostate cancer. Dr....Read More