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Kamiesh Yadav

Kamlesh Yadav

Understanding the biology of how prostate cancer cells develop resistance to drugs, and how different drugs interact with one another will lead to the development of drug combinations that significantly...Read More

Wilson_Kathy(enh1)

Kathryn Wilson

Metastatic prostate cancer is essentially incurable and the most common metastatic site for prostate cancer is the bone. Understanding the interactions between prostate cancer cells and the bone environment will...Read More

Heemers_Hannelore(low)

Hannelore Heemers

Androgens (testosterone and related sex hormones) drive the growth and survival of prostate cancer. For almost seven decades, reducing androgens in patients with prostate cancer has been a widely utilized...Read More

Wang_Yu(enh1)

Yu Wang

Castrate-resistant prostate cancer (CRPC) is an aggressive, lethal form of prostate cancer that recurs after initial treatment with androgen deprivation therapy (ADT). ADT targets the androgen receptor (AR), the primary...Read More

Wang_Li

Li Wang

The identification of biomarkers to stratify risk for prostate cancer patients remains an unmet medical need. Dr. Li Wang is using bioinformatics methods to identify immune cell gene expression signatures...Read More

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Julia Hayes

Prostate Specific Antigen (PSA) screening is widely used to assist the early diagnosis of prostate cancer. However, benefits of PSA screening are controversial. Dr. Hayes proposes to develop a model...Read More

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Daniel Hamstra

The molecular processes that predict who will have a local recurrence after radiation therapy and who will not are not precisely understood. New evidence suggests that prostate tumors with abnormal...Read More

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Hans Hammers

Dr. Hammers has initiated a project to determine the mechanisms of resistance of advanced prostate cancer to angiogenesis inhibitors, like Avastin, that block the development of new blood vessels that...Read More

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David S. Finley

Obesity increases the risk of developing prostate cancer and most major cancers. New data suggests that adipose tissue (body fat), now considered an “organ,” is capable of secreting numerous molecules...Read More

Den_Robert(low)

Robert Den

Radiation therapy in combination with medicines that block testosterone (hormonal therapy) is a common treatment for locally advanced prostate cancer. However, a subset of these patients will not be cured...Read More