2019 PCF Challenge Award
Targeting the Translational Oncogenic Program Through eIF4E and eIF4A in Metastatic Castration Resistant Prostate Cancer Using Three Novel Small Molecule Inhibitors
Principal Investigator: Hao Nguyen, MD, PhD (University of California, San Francisco)
Co-Investigators: Davide Ruggero, PhD (University of California, San Francisco), Peter Carroll, MD, MPH (University of California, San Francisco)
2019 PCF Challenge Award
HOXB13 as a Therapeutic Target in Prostate Cancer
Principal Investigator: Donald McDonnell, PhD (Duke University)
Co-Investigators: Damian Young, PhD (Baylor College of Medicine), Ryan Soderquist, PhD (Duke University), Andrew Armstrong, MD (Duke University), Kris Wood, PhD (Duke University)
2019 PCF Challenge Award
Discovering drivers of treatment response and resistance in the multi-focal prostate tumor microenvironment
Principal Investigators: Joshua Lang, MD, MSc (University of Wisconsin), Steve Cho, MD (University of Wisconsin), Kenneth Pienta, MD (Johns Hopkins University), David Jarrard, MD (University of Wisconsin), David Quigley, PhD (University of California, San Francisco)
Co-Investigators: David Beebe, PhD (University of Wisconsin), John Denu, PhD (University of Wisconsin), Shane Wells, MD (University of Wisconsin), Wei Huang, MD (University of Wisconsin), Alejandro Roldán-Alzate, PhD (University of Wisconsin), Tyler Bradshaw, PhD (University of Wisconsin), Irene Ong, PhD (University of Wisconsin), David Kosoff, MD (University of Wisconsin), Sarah Amend, PhD (Johns Hopkins University)