2021 Durden Foundation-PCF Challenge Award
Project Title: Single Cell Profiling to Identify Mechanisms of Tumor Progression in Metastatic Prostate Cancer
Principal Investigators:
Joshi Alumkal, MD (University of Michigan)
Euisik Yoon, PhD, MSc (University of Michigan)
Co-Investigators: Thomas Westbrook, MD (University of Michigan), Arvind Rao, PhD (University of Michigan), Arul Chinnaiyan, MD, PhD (University of Michigan), Zachery Reichert, MD, PhD (University of Michigan), Todd Morgan, MD (University of Michigan)
2021 PCF Challenge Award
Project Title: Exploiting BH3 Mimetic Drugs to Drive Apoptosis in Prostate Cancer
Principal Investigators:
Steven Balk, MD, PhD (Harvard: Beth Israel Deaconess Medical Center)
Johann de Bono, MD, PhD (Institute of Cancer Research)
Eva Corey, PhD (University of Washington)
Yuzhuo Wang, PhD (University of British Columbia)
Co-Investigators: Adam Sharp, MD, PhD (Institute of Cancer Research), Andreas Varkaris, MD, PhD (Beth Israel Deaconess Medical Center), David Einstein, MD (Beth Israel Deaconess Medical Center)
2021 Movember-Distinguished Gentleman’s Ride-PCF Challenge Award
Project Title: Leveraging Epigenomics to Target Acquired Vulnerabilities in Treatment Resistant Prostate Cancer
Principal Investigator:
Matthew Freedman, MD (Harvard: Dana-Farber Cancer Institute)
Co-Investigators: Mark Pomerantz, MD (Dana-Farber Cancer Institute), Wilbert Zwart, PhD (The Netherlands Cancer Institute), Sylvan Baca, MD, PhD (Dana-Farber Cancer Institute), Tesa Severson, PhD (Netherlands Cancer Institute)
2021 Credit Suisse, Republic National Distributing Company (RNDC), Trailsend Foundation, PCF Challenge Award
Project Title: Targeting the PTGES3-AR axis in Advanced Prostate Cancer
Principal Investigators:
Luke Gilbert, PhD (University of California, San Francisco)
Felix Feng, MD (University of California, San Francisco)
Kevan Shokat, PhD (University of California, San Francisco)
Michelle Arkin, PhD (University of California, San Francisco)
Co-Investigators: Haolong Li, PhD (University of California, San Francisco)
2021 Janssen-PCF VAlor Challenge Award
Project Title: PARPi Response Evaluation for Clinical Impact and Scientific Innovation in Oncology: The PRECISION Registry
Principal Investigators:
Veda Giri, MD (Thomas Jefferson University)
Susan Halabi, PhD (Duke University)
Alexander Wyatt, PhD (University of British Columbia)
Co-Investigators: Rhonda Bitting, MD (Duke University), Christopher McNair, PhD (Thomas Jefferson University)