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Dr. Holt earned a BA in Biology..
Sarah Holt, PhD:
Fred Hutchinson Cancer Research Center – Seattle, WA
Systematic identification of genetic variants within AR..
Junjie Feng, PhD:
Wake Forest University
Mentor:
Jiangfeng Xu, MD, PhD
Dr. Harzstark earned a BS degree in..
Andrea Harzstark, MD:
University of California, San Francisco – San Francisco, CA
Nanotargeting Estrogen Receptor regulated Long Non Coding..
Dimple Chakravarty, PhD, DVM:
Weill Cornell Medical College
Mentor:
Mark Rubin, MD
Dr. Harui earned a BS in Pharmaceutical..
Airi Harui, PhD:
University of California, Los Angeles – Los Angeles, CA
Dr. Guzzo earned a BS in Biology..
Thomas Guzzo, MD:
University of Pennsylvania – Philadelphia, PA
Prostate cancer diagnosis and precision medicine treatment..
Jeremy Durack, MD, MS:
Memorial Sloan-Kettering Cancer Center
Mentor:
Howard Scher, MD
Proposal Title:
Rapid Spectroscopic Assessment of Targeted Prostate Cancer Biopsy Sufficiency at the Point-of-Care
Growing clinical evidence suggests that a majority..
Shalini S. Yadav, PhD:
Mount Sinai School of Medicine
Mentors:
Ashutosh Tewari, MD
Project Title:
Intratumor Heterogeneity (ITH) in Prostate Cancer
Dr. Frank earned his certification in Nuclear..
Steven Frank, MD:
The University of Texas MD Anderson Cancer Center – Houston, TX
Treatment of advanced, metastatic prostate cancer, although..
Daniel Thorek, PhD:
Johns Hopkins University
Mentors:
David Scheinberg, MD, PhD and Steve Larson, MD
Project Title:
Alpha-particle therapy by 225Actinium-labeled prostate kallikrein-specific antibody to eradicate advanced disease
Dr. Feldman earned a BA degree in..
Adam Feldman, MD:
Massachusetts General Hospital Cancer Center – Boston, MA
IGF (Insulin-like Growth Factor) receptor is dysregulated..
Nicole Simone, MD:
Thomas Jefferson University
Mentors:
Adam Dicker, MD, PhD, Karen Knudsen, PhD and Peter Carroll, MD
Project Title:
Metabolic approaches for targeting multiple components of the IGF-1R pathway in prostate cancer
Deficiencies in the repair of DNA are..
Matthew Schiewer, PhD:
Thomas Jefferson University
Mentor:
Karen Knudsen, PhD
Project Title:
Determining the translation capacity of the PARP-1/AR axis in prostate cancer
Dr. Efsathiou earned both MD and PhD..
Eleni Efstathiou, MD, PhD:
The University of Texas MD Anderson Cancer Center – Houston, TX
Low vitamin D levels in blood have..
Jennifer Rider, ScD:
Harvard School of Public Health
Mentors:
Lorelei Mucci, ScD and Myles Brown, MD
Project Title:
The immunomodulatory and androgen-associated actions of vitamin D in prostate cancer
Colin Pritchard, MD, PhD:
University of Washington
Mentors:
Peter Nelson, MD
Project Title:
Targeting the ‘Hypermutated Subtype’ of Prostate Cancer: From Mechanism to Implementation of Genomic Testing for Precision Therapy”
Dr. Dehm completed a BS and PhD..
Scott M. Dehm, PhD:
Masonic Cancer Center, University of Minnesota – Minneapolis, MN
Dr. Choudhury earned a BA in Chemistry..
Atish Dipankar Choudhury, MD, PhD:
Dana-Farber Cancer Institute – Boston, MA
Dr. Bismar earned an MD degree from..
Tarek Bismar, MD:
University of Calgary – Canada
Dr. Attard earned an MD degree from..
Gerhardt Attard, MD, PhD:
The Institute for Cancer Research – London, UK
Dr. Arredouani earned a BS Degree in..
Mohamed S. Arredouani, PhD:
Beth Israel Deaconess Hospital – Boston, MA
Systems biology is a computational-based inter-disciplinary field..
Antonina Mitrofanova, PhD:
Rutgers, The State University of New Jersey
Mentor:
Michael Shen, PhD
Project Title:
A systems biology approach to identify and evaluate novel drug targets for aggressive prostate cancer
LncRNAs (long non-coding RNAs) are a form..
Rohit Mehra, MD:
University of Michigan School of Medicine
Mentor:
Arul Chinnaiyan, MD, PhD
Project Title:
Clinicopathological characterization of novel lncRNAs in prostate cancer risk stratification
Differentiating indolent from aggressive prostate tumors is..
Marcin Cieslik, PhD:
University of Michigan
Mentor:
Arul Chinnaiyan, MD, PhD
Proposal Title:
Clinical Implications of Expressed Pseudogene Transcripts in Metastatic Castration-Resistant Prostate Cancer
Certain oncogenic molecules in prostate cancer cells..
Theodoros Karantanos, MD:
MD Anderson Cancer Center
Mentors:
Timothy Thompson, PhD and Christopher Logothetis, MD
Project Title:
The role of aerobic glycolysis in the development of castrate resistant prostate cancer
T cells are a type of immune..
W. Nathaniel Brennen, PhD:
The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Mentors:
John Isaacs, PhD, Charles Drake, MD, PhD
Proposal Title:
T cells Engineered to Selectively Deliver a PSA-activated Protoxin to Sites of Advanced Prostate Cancer
Dr. Armstrong earned a BS in Biomedical..
Andrew Armstrong, MD, ScM:
Duke University – Durham, NC
Preclinical assessment of mechanisms of resistance to..
Vivek Arora, MD, PhD:
Washington University
Mentor:
Charles Sawyers, MD
Project Title:
Defining strategies to overcome enzalutamide (Xtandi) resistance
Approximately 25% of patients who fail Xtandi..
Jennifer Bishop, PhD:
University of British Columbia
Mentors:
Martin Gleave, MD and Amina Zoubeidi, PhD
Project Title:
Regulation of cell plasticity by the androgen receptor: A novel mechanism of enzalutamide (Xtandi) resistance
The organization of DNA into super-structures is..
Irfan Asangani, PhD:
University of Michigan
Mentor:
Arul Chinnaiyan, MD, PhD
Project Title:
Characterization and therapeutic targeting of MMSET in prostate cancer
Engraftment of prostate cancer in bone heralds..
Charles Chan, PhD:
Stanford University School of Medicine
Mentors:
Irving Weissman, MD and Michael Longaker, MD
Project Title:
Identification and therapeutic targeting of cancer stem cell niche interactions in metastatic prostate bone marrow disease
An unmet medical need is the control..
Chia-Yi Chu, PhD:
Cedars-Sinai Medical Center
Mentor:
Leland Chung, PhD
Project Title:
Metastasis-initiating cells (MICs) as predictors of lethal progression of human prostate cancer
Molecular imaging of prostate cancer to determine..
Michael Evans, PhD:
University of California, San Francisco
Mentors:
Charles Sawyers, MD and Jason Lewis, PhD
Project Title:
Exploiting the genetics of advanced prostate cancer for tumor detection and therapy with transferrin-based radionuclides