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Jason A. Efstathiou
Jason A. Efstathiou
2013 Astellas Scientific and Medical Affairs, Inc. and Medivation, Inc. – PCF Young Investigator Award
Jason A. Efstathiou, MD, DPhil:
Massachusetts General Hospital
Mentor:
Matthew R. Smith, MD, PhD
Project Title:
Predictors of Response and Failure to Radiotherapy for Prostate Cancer in a Randomized Trial
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Geraldine Gueron
Proteomics is the study of proteins in..
Geraldine Gueron
2013 Stanley Zax-PCF Young Investigator
Geraldine Gueron, PhD:
Iquibicen-Conicet (Argentina)
Mentor:
Elba Vazquez, PhD
Project Title:
Proteome-base biomarkers in prostate cancer: protein profiling using mass spectrometry, bioinformatics based approach and tissue microarray technology
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Lauren Harshman
Immunotherapy has come of age with the..
Lauren Harshman
2013 PCF Young Investigator
Lauren Harshman, MD
Dana-Farber Cancer InstituteMentors:
Philip Kantoff, MD and Christopher Sweeney, MBBS
Project Title:
Clinical exploration of innovative targeted and immune modulating therapies in prostate cancer
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Emmanuel Antonarakis
Understanding resistance to new treatments for advanced,..
Emmanuel Antonarakis
2013 Steve Wynn-PCF Young Investigator
Emmanuel Antonarakis, MD:
Johns Hopkins University School of Medicine
Mentors:
Michael Carducci, MD and Jun Luo, PhD
Project Title:
Understanding mechanisms of response and resistance to abiraterone (Zytiga) and enzalutamide (Xtandi) in men with metastatic castration-resistant prostate cancer, by interrogation of tumor biopsies for androgen receptor splice variants.
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Syed Adnan Ali
Over 1 million prostate biopsies are performed..
Syed Adnan Ali
2013 LeFrak Family-PCF Young Investigator
Syed Adnan Ali, MD:
Mount Sinai School of Medicine
Mentor:
Ashutosh Tewari, MD
Project Title:
Intratumor Heterogeneity (ITH) in Prostate Cancer
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Shuang Zhao, MD
Long non-coding RNAs (lncRNAs) such as PCAT1..
Shuang Zhao, MD
2015 James Litinsky–PCF Young Investigator Award
Institution:
University of Michigan
Mentors:
Arul Chinnaiyan, MD, PhD; Felix Feng, MD
Proposal Title:
Investigating Long Noncoding RNAs in Aggressive Prostate Cancer
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Rendong Yang
Next generation sequencing (NGS) is a growing..
Rendong Yang
2015 Genomic Health–PCF Young Investigator
Rendong Yang, PhD:
University of Minnesota
Mentor:
Scott Dehm, PhD
Proposal Title:
Delineating Coding and Regulatory Indels in Prostate Cancer
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Adam Sowalsky
Genomic analysis of cancer tissue has enabled..
Adam Sowalsky
2015 National Cancer Institute–PCF Young Investigator
Adam Sowalsky, PhD:
National Cancer Institute
Mentors:
Kathleen Kelly, PhD; William Dahut, MD
Proposal Title:
Investigations into the Mechanisms of Resistance to Enzalutamide in CRPC
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Prasanna Sooriakumaran
As life expectancy rises, greater numbers of..
Prasanna Sooriakumaran
2015 Howard Shore–PCF Young Investigator
Prasanna Sooriakumaran, MBBS, PhD:
University of Oxford
Mentor:
Freddie C. Hamdy, MD
Proposal Title:
Improving Quality of Care for Men with Skeletal Metastases from Prostate Cancer: Defining the Burden-of-Treatment and its Management, and Developing Models to Predict Quality-of-Life
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Shabnam Shalapour
Cancer is characterized by accumulation and loss..
Shabnam Shalapour
2015 David Yurman–PCF Young Investigator
Shabnam Shalapour, PhD:
University of California, San Diego
Mentor:
Michael Karin, PhD
Proposal Title:
Development of Immunosuppressive Plasmocytes that Interfere with T-Cell-Dependent Immunogenic Chemotherapy in Prostate Cancer
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Saul Priceman
Supplementing a patient’s immune response by engineering..
Saul Priceman
2015 Lori Milken–PCF Young Investigato
Saul Priceman, PhD:
City of Hope National Medical Center
Mentor:
Stephen Forman, MD
Proposal Title:
Targeting Metastatic Prostate Cancer with PSA-Specific Chimeric Antigen Receptor-Engineered T-Cells
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Sean McGuire
New hormonal treatments for prostate cancer such..
Sean McGuire
2015 John Paulson–PCF Young Investigator
Sean McGuire, MD, PhD:
Baylor College of Medicine
Mentor:
Bert O’Malley, MD
Proposal Title:
Targeting the Mitochondrial Pyruvate Carrier in Castration- Resistant Prostate Cancer
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Ravi Madan
Immune checkpoint inhibitors “take the brakes” off..
Ravi Madan
2015 National Cancer Institute– PCF Young Investigator
Ravi Madan, MD:
National Cancer Institute
Mentor:
James Gulley, MD, PhD
Proposal Title:
Using A Therapeutic Cancer Vaccine to Enhance Anti-PD-1 Therapy Prior to Prostatectomy
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Zhenfei Li
While most men with prostate cancer initially..
Zhenfei Li
2015 Steve Schwarzman–PCF Young Investigator
Zhenfei Li, PhD:
Cleveland Clinic Foundation
Mentors:
Nima Sharifi, MD; Eric Klein, MD
Proposal Title:
A Novel Abiraterone Metabolite as a Predictive Biomarker for Clinical Response to Abiraterone
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John Kyung Lee
A highly aggressive subtype of treatment-resistant prostate..
John Kyung Lee
2015 Lori Milken–PCF Young Investigator
John Kyung Lee, MD:
University of Washington
Mentor:
Owen Witte, MD
Proposal Title:
Therapeutic Targeting of N-Myc-Driven Human Small Cell Neuroendocrine Prostate Cancer
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Vishal Kothari
New therapeutic targets and prognostic biomarkers for..
Vishal Kothari
2015 Gerry Lenfest–PCF Young Investigator
Vishal Kothari, PhD:
University of Michigan
Mentors:
Arul Chinnaiyan, MD, PhD; Felix Feng, MD
Proposal Title:
Investigating DNAPK as a Therapeutic Target and a Prognostic Biomarker in Castration-Resistant Prostate Cancer
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Won Kim
The emergence of treatment-resistant prostate cancer (CRPC)..
Won Kim
2015 Dendreon Pharmaceuticals–PCF Young Investigator
Won Kim, MD:
University of California, San Francisco
Mentors:
Charles Ryan, MD; Eric Small, MD
Proposal Title:
Dissecting Variant Androgen Signaling Phenotypes to Guide Treatment Selection in Abiraterone Acetate and Enzalutamide-Resistant Prostate Cancer
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Joseph Ippolito
Metabolic oxidative phosphorylation (OXPHOS) is a biochemical..
Joseph Ippolito
2015 Victoria & Vinny Smith, Eustace Wolfington,
and Ali & Joe Torre–PCF Young InvestigatorJoseph Ippolito, MD, PhD:
Washington University School of Medicine in St. Louis
Mentors:
Jeffrey Arbeit, MD; Farrokh Dehdashti, MD
Proposal Title:
Characterizing and Imaging Metabolic Symbiosis in Castrate- Resistant Prostate Cancer
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Howard Scher
Cell signaling in cancer causes uncontrolled cell..
Howard Scher
Howard Scher, MD –:
Memorial Sloan-Kettering Cancer Center
Development of Combined Inhibition of AR and PI3K Signaling as a Therapeutic Strategy for Advanced Prostate CancerCo-Investigators:
Charles Sawyers, MD; Brett Carver, MD; Neal Rosen, MD, PhD
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Amanda Hargrove
Long noncoding RNAs (lncRNAs) play a critical..
Amanda Hargrove
2015 Brent Nicklas–PCF Young Investigator
Amanda Hargrove, PhD:
Duke University
Mentors:
Hashim Al-Hashimi, PhD; Peter Dervan, PhD
Proposal Title:
Targeting the lncRNA SChLAP1 in Aggressive Prostate Cancer by the Assembly of Multivalent Small Molecule Inhibitor
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Justin Drake
Men with progressive metastatic prostate cancer are..
Justin Drake
Justin Drake, PhD:
Rutgers University Cancer Institute of New Jersey
Mentor:
Robert DiPaola, MD
Proposal Title:
Elucidating Kinase Activation Pathways in Advanced Prostate Cancer
2015 Adrianne & Jerry Cohen, Larry Gagosian, and Pablo Legorreta–PCF Young Investigator
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Martin Sanda
Dr. Sanda and his cross-disciplinary team of..
Martin Sanda
Martin Sanda, MD –:
Beth Israel Deaconess Medical Center
Nanoparticle-Targeted Peptide Vaccines for Prostate Cancer: The Harvard – Hopkins – Carolina ConsortiumCo-Investigators:
Joseph M DeSimone, PhD; Simon M Arredouani, PhD; Charles Drake, MD, PhD
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William G. Nelson
One of the causes for the initiation..
William G. Nelson
William G. Nelson, MD, PhD – :
Johns Hopkins Medicine
Induction of Synthetic Lethality with Epigenetic therapy (ISLET) for Systemic Treatment of Prostate CancerCo-Investigators:
Srinivasan Yegnasubramanian, MD, PhD; Jun O. Liu, PhD; Stephen B. Baylin, MD; Michael A. Carducci, MD; Martin J. Aryee, PhD
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Christopher J. Logothetis
Despite initial response, most prostate cancers will..
Christopher J. Logothetis
Christopher J. Logothetis, MD –:
The University of Texas MD Anderson Cancer Center Mechanisms of Resistance to Androgen Biosynthesis Inhibition in Castration-Resistant Prostate Cancer Bone Metastases
Co-Investigators:
Gary Gallick, PhD; Sankar Maity, PhD; Randall Millikan, MD, PhD; Mark Bedford, PhD; Eleni Efstathiou, MD, PhD
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Heather Cheng
Although family history is well-established as a..
Heather Cheng
Heather Cheng, MD, PhD:
University of Washington
Mentor:
Peter Nelson, MD
Proposal Title:
Identifying High-Penetrance Prostate Cancer Risk Genes: Leveraging Families for Next Generation Discovery and Prevention
2015 Kelsey Dickson–PCF Young Investigator
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Dr. Glenn Liu
As prostate cancer advances and spreads, it..
Dr. Glenn Liu
Dr. Glenn Liu, MD –:
UW Carbone Cancer Center Imaging Biomarkers of Treatment Response Using NaF PET/CT Imaging: a Prostate Cancer Clinical Trials Consortium (PCCTC) Effort
Co-Investigators:
Michael Morris; William Dahut, MD; Steven Larson, MD; Peter Choyke, MD; Robert Jeraj, PhD
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Philip G. Febbo
Drs. Febbo and Higano propose a phase..
Philip G. Febbo
Philip G. Febbo, MD –:
University of California, San Francisco
Understanding the Clinical and Radiological Impact of XL184 through Treatment ScienceCo-Investigators:
Celestia Higano, MD, Beatrice Knutson, PhD, Peter Nelson, MD, Edwin Posadas, MD, Ravi Salgia, MD, Evan Yu, MD
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Leland W.K. Chung
There are very few effective medications for..
Leland W.K. Chung
Leland W.K . Chung, PhD –:
Cedars-Sinai Medical Center
Targeting Cell Death Programs in the Tumor and its MicroenvironmentCo-Investigators:
Edwin Posadas, MD; Neil Bhowmick, PhD; Hyung L Kim, MD;
Andre Rogatko, PhD; Beatrice Knudsen, MD, PhD; Stuart Holden, MD; Mahul B. Amin, MD; Martin Gleave, MD; Michael Freeman, PhD; Daqing Wu, PhD; Matthew Bui, MD
