Geraldine Gueron

About Geraldine Gueron

• Proteomics is the study of proteins in a cell and their interactions with each other.
• The overall goal of this research is to use proteomics for the identification of predictive prostate cancer disease biomarkers.
• Dr. Gueron has demonstrated that a protein designated Heme Oxygenase-1 (HO-1) is involved in prostate cancer etiology and that it directly interacts with other cancer-causing proteins involved in cell signaling.
• Studying the interaction of HO-1 and other cell signaling molecules is significant because it is believed to regulate the engine of prostate cancer – the androgen receptor.

What this means for patients: This novel targeted proteomics study may do two things: 1) develop a laboratory test that will predict the presence of potentially lethal prostate cancer and 2) discover targets for the treatment of advanced metastatic prostate cancer.