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2015-YI-PRASANNA-SOORIAKUMARAN

Prasanna Sooriakumaran

As life expectancy rises, greater numbers of older men with skeletal metastases from prostate cancer suffer higher treatment burdens. The current standard-of-care, androgen deprivation therapy (ADT), causes morbidity and might...Read More

2015-YI-SHABNAM-SHALAPOUR

Shabnam Shalapour

Cancer is characterized by accumulation and loss of normal cellular regulatory processes, leading to expression of tumor-specific molecules (antigens). The tumor microenvironment also causes exhaustion of the patient’s immune response...Read More

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Michael Schweizer, MD

Dr. Michael Schweizer is an Assistant Professor at the Department of Medicine at the Division of Medical Oncology at the University of Washington School of Medicine. He also is a...Read More

2015-YI-SAUL-PRICEMAN

Saul Priceman

Supplementing a patient’s immune response by engineering their killer white blood cells (CAR T-cells) to recognize, bind to, and eliminate the tumor is a new and transformational area of cancer...Read More

2015-YI-SEAN-MCGUIRE

Sean McGuire

New hormonal treatments for prostate cancer such as Xtandi® and Zytiga® are effective, but patients invariably become resistant to these medications. Dr. Sean McGuire’s innovative research is evaluating potential therapeutic...Read More

2015-YI-RAVI-MADAN

Ravi Madan

Immune checkpoint inhibitors “take the brakes” off a patient immune response, resulting in immune elimination of the cancer. Patients with melanoma, renal, bladder, lymphoma and lung cancers have been successfully...Read More

2015-YI-ZHENFEI-LI

Zhenfei Li

While most men with prostate cancer initially respond well to androgen deprivation therapies (ADT) such as Zytiga®, some do not, and patients inevitably develop resistance to treatment. Recent research has...Read More

john-k-lee

John Kyung Lee

A highly aggressive subtype of treatment-resistant prostate cancer has been increasingly diagnosed in men who have suffered from the disease and were treated with androgen deprivation therapy. Small cell neuroendocrine...Read More

2015-YI-VISHAL-KOTHARI

Vishal Kothari

New therapeutic targets and prognostic biomarkers for treatment-resistance prostate cancer (CRPC) would greatly improve outlook and decrease mortality rates for men with advanced forms of this disease. Recent research has...Read More

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Won Kim

The emergence of treatment-resistant prostate cancer (CRPC) is an inevitable outcome for men treated with androgen receptor (AR) targeted therapies. At present, the biology of prostate cancer treatment resistance is...Read More