David Heber, MD, PhD
Development of an Ex Vivo Bioassay to Examine Modulation of PSA-Positive Macrophage Invasiveness and Inflammatory Activities in Prostate Cancer Patients with Abdominal Obesity—The Identification of New Biomarkers May Be Able...Read More
Amado Zurita
Dr. Zurita’s research goal is to improve the detection of prostate cancer bone metastasis and ultimately to prevent bone metastasis, an event contributing to the lethality of the disease. A...Read More
Barbara Graves, PhD
ETS Protein Targets in Prostate Cancer—Understanding Gene Activity that Likely Causes Up to 60 Percent of Prostate Cancer Cases Can Open Door to New Drug Development Over-expression of Ets genes,...Read More
Amina Zoubeidi
Dr. Zoubeidi’s research is focused on determining the function of a molecule called Heat Shock Protein 27 (Hsp27), which has been implicated as a promoter of tumor cell movement, invasion...Read More
Shelton Earp, MD
Application of Nanotechnology to Novel Models of Prostate Cancer—Nanoscale Fabrication Technology May Provide New Modeling Capabilities and Therapies to Arrest Lethal PCa Progression This program has discovered that a molecule...Read More
Neha Vapiwala
Approximately 30% of patients treated for what is believed to be localized, non-metastatic prostate cancer will progress to advanced disease. One challenge is to identify the mechanisms of therapy resistance...Read More
Jay Shendure
Currently, a comprehensive understanding of the genetic events that cause prostate cancer initiation and progression has not been technologically possible. Dr. Shendure has developed a new biotechnology to exhaustively sequence...Read More
Jennifer Schutzman
Many genes that are critical for proper embryonic development are disregulated in human cancers. For example, Sprouty genes (Spry1 and Spry2) are both critical for neuronal and early prostate gland...Read More
Philip Saylor
Hormonal therapy for prostate cancer causes weight gain, adversely alters cholesterol and other blood lipids, and is associated with increased risk for heart attacks and the development of type II...Read More
Edwin Posadas
Dr. Posadas’ research goal is to identify the molecular mechanisms of prostate cancer metastasis. A protein called FYN, which is a member of a cancer-causing gene family, was identified in...Read More