Tanya Stoyanova
Few options remain for prostate cancer patients who have failed to respond to androgen deprivation therapy. New therapeutic targets and treatments are desperately needed. Dr. Tanya Stoyanova is investigating two...Read More
Jennifer Doll, PhD
Periprostatic Fat as a Promoter of Prostate Cancer Progression Obesity and high fat diets are associated with more aggressive prostate cancer. Yet, the mechanism underlying this association remains unclear. Dr....Read More
Antoinette Perry
A critical unmet need for prostate cancer research is the identification of aggressive tumors at an early stage while potentially curable and distinguishing them from indolent tumors to avoid over-treatment...Read More
Brendan Curti, MD
Augmenting OX40 Immunotherapy in Men with Advanced Prostate Cancer Dr. Curti and his team are pioneers in the preclinical and clinical development of a new immunotherapy that activates the anti-tumor...Read More
Matthias Stephan
The immune system is a powerful natural defense system that targets and kills cells considered by the host to be dangerous. Tumors survive because of their ability to evade or...Read More
Kathryn L. Penney
The Gleason score (derived from the microscopic appearance of prostate tumor tissue) is currently the only reliable predictor for prostate cancer prognosis and treatment. Dr. Penney has previously identified a...Read More
Tamara Lotan, MD
Dr. Tamara Lotan is an associate professor of pathology and oncology at the Johns Hopkins University School of Medicine. Her area of clinical expertise is urologic pathology. Dr. Lotan received...Read More
Daniel Spratt
Some prostate cancer patients who undergo radiation therapy do not derive a significant benefit from this treatment. The androgen receptor (AR) is the primary factor mediating growth and survival in...Read More
Richard Lee
Circulating Tumor Cells (CTCs) detach from metastatic tumor sites and can be isolated from patient blood specimens. CTCs are good predictors of metastatic tumor biology. Dr. Lee proposes to study...Read More
Gustavo Ayala, MD
Targeting Neurogenesis in Prostate Cancer The prostate gland is rich in nerves and proteins that support nerve growth (neural growth factors). Studies from Dr. Ayala’s group have demonstrated that prostate...Read More